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    APOE and the Risk of Developing Late Onset Alzheimer's Disease: A Research Proposal

    Number of Pages: 9


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    This 9 page paper considers the issue of the presence of APOE and the risk of the development of late onset Alzheimer's disease. This paper is a research proposal for this problem and outlines the study of a possible subject population. Bibliography lists 5 sources.

    Name of Research Paper File: MH11_MHAlzhe2.rtf

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    lists 5 sources. MHAlzhe2.rtf APOE and the Risk of Developing Late Onset Alzheimers Disease: A Research Proposal Written for The Paper  Store, Inc. by 09/2001 Please ABSTRACT For over a decade, researchers have considered the issue of the presence of  genetic factors as predictors of late-onset AD. This study proposal is designed to consider the perspectives presented in the current literature and the viewpoints of researchers on a variety  of levels, to consider whether APOE is a substantial predictor. Further, this research proposal focuses on the importance of APOE even in the midst of research that suggests  that other genetic factors may also play a role in predicting onset, including the age of onset. This proposal focuses on the assessment of APOE and the comparative view  of the current literature as a basis for understanding arguments that other genetic factors have substantial importance as predictors of onset of AD. INTRODUCTION Since the early 1990s,  a number of studies have assessed possible causative factors of Alzheimers disease (AD), and possible risk factors for the development of late onset AD. Initially, researchers considered environmental factors,  cognitive issues and mental health factors, all of which have been deemed contributing factors in the development of this disease (APA, 1994). Over the course of the last ten  years, though, researchers have attempted to determine the impact of certain genetic factors as a predictor of late onset AD, including the presence of the apoliprotein E (APOE). Many  studies have been conducted about the importance of APOE as a predictor for late onset AD, but questions still remain regarding the accuracy of the argument that the presence of 

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